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Spacing Pfizer COVID shots boosts antibody levels after initial drop -study

Spacing Pfizer COVID shots boosts antibody levels after initial drop -study

13 Sept 08:06 Key points summarised by AI
  • A longer interval between Pfizer COVID-19 vaccine doses significantly elevates overall neutralizing antibody levels post-second dose compared to a shorter gap.
  • Crucially, a single dose with a longer gap results in a sharp, unmaintained drop in antibody levels, especially against the Delta variant, underscoring the necessity of the second dose.
  • Despite lower overall T-cell levels with extended gaps, a higher proportion of "helper" T cells, vital for long-term immune memory, were observed.
  • The findings advocate for delaying the second dose to achieve more durable immunity, influencing Britain's current recommendation of an 8-week dosing interval.
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