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Third booster with half dose of Pfizer vaccine as effective as full dose - study

Third booster with half dose of Pfizer vaccine as effective as full dose - study

14 Sept 02:52 Key points summarised by AI
  • Thailand's Siriraj Institute of Clinical Research recommends a half-dose Pfizer booster shot after two AstraZeneca doses, citing its comparable effectiveness to a full dose.
  • A study found that a half-dose Pfizer booster generates antibody levels nearly as high as a full dose, particularly following initial Sinovac or AstraZeneca vaccinations.
  • Specifically, a half-dose Pfizer booster achieved 1,962 BAU/ml, closely approaching the 2,377 BAU/ml from a full dose, demonstrating robust antibody production.
  • For individuals with two Sinovac jabs, a half-dose Pfizer booster yielded superior antibody levels against the Delta variant (499) compared to a full dose (411).
  • The research confirmed that participants experienced only mild to moderate undesirable side effects across the tested booster regimens.
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