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Scientists discover how air pollution triggers lung cancer

Scientists discover how air pollution triggers lung cancer

10 Sept 07:29 Key points summarised by AI
  • Scientists identify a novel mechanism: air pollution (PM2.5 particles) triggers lung cancer in non-smokers by activating dormant DNA mutations through inflammation.
  • This "wound-healing response" caused by pollution transforms pre-existing genetic mutations (e.g., in EGFR and KRAS genes) into active cancer, challenging prior understanding of carcinogen action.
  • The breakthrough paves the way for new cancer prevention strategies, including potential "molecular cancer prevention" pills designed to block inflammation and mitigate cancer risk.
  • Hailed as "revolutionary," the research underscores the urgent global imperative to combat air pollution, a "hidden killer" with significant links to human health and climate change.
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