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Nobel winner's ingenious chemistry could lead to cancer breakthroughs
AI In-brief 14 Sept 08:30

Nobel winner's ingenious chemistry could lead to cancer breakthroughs

  • Nobel laureate Carolyn Bertozzi developed "bioorthogonal chemistry," a groundbreaking method allowing precise chemical reactions to occur within living systems without disrupting natural biological processes.
  • Her technique involves two 'Lego-like' chemical components: one integrates into target cells (like cancer cells), and the second, often carrying a fluorescent marker or drug, specifically clicks into place.
  • This innovation is revolutionizing cancer treatment development, enabling new strategies such as 'lawnmower' drugs that remove protective sugars from cancer cells to expose them to the immune system.
  • It also facilitates highly targeted therapies, where drugs are delivered with extreme precision directly to tumors, minimizing exposure of healthy tissues to toxic chemicals and promising significant advancements in human health.
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